Substance Use Disorder Grants for Nonprofits

GrantStation’s exclusive database features 516 active funding opportunities giving towards this area of interest, all accepting requests from new grantseekers!

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Solcz Family Foundation

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Application Deadline:
  • Proposal forms: May 22, 2026
  • Applications: July 3, 2026
     

The Solcz Family Foundation is committed to improving the welfare of the Windsor-Essex, ON, community, with a focus on supporting projects and programs that provide opportunities for children,…

Phoenixville Community Health Foundation

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Application Deadline:
  • Annual Grants: May 22, 2026
  • Mini Grants: None
  • Inquiries may be submitted year-round
     
Grant Range:
$1000 - $2214415
Average Grant:
$260652

The mission of Phoenixville Community Health Foundation is to improve the health and quality of life in selected townships and boroughs in the greater Phoenixville area of Chester and Montgomery…

Grant Healthcare Foundation

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Application Deadline:

Letters of inquiry: May 22, 2026
Invited applications: September 4, 2026

Grant Range:
$15000 - $50000
Average Grant:
$28214

The Grant Healthcare Foundation supports nonprofit organizations in the Chicago, IL, metropolitan area that focus on healthcare.

The Foundation supports the following activities:

    …

Kendrick Foundation

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Application Deadline:
  • Letter of Intent: May 22, 2026
  • Full application due: August 7, 2026
Grant Range:
$616 - $506681
Average Grant:
$31773

The Kendrick Foundation invests in conditions that support the physical and mental health of all Morgan County, IN, residents.

The Foundation seeks to partner with strong, innovative…

Paso Del Norte Health Foundation

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Application Deadline:

Letters of Intent: May 26, 2026

Grant Range:
$1500 - $1250000
Average Grant:
$81558

The Paso del Norte Health Foundation promotes health and prevents disease through leadership in health education, research, and advocacy in the greater El Paso region.

Priority areas…

Hogg Foundation for Mental Health

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Application Deadline:
  • Libraries Supporting Community Mental Health: April 29, 2026 Registration due; May 6, 2026 Proposal due
  • Rio Grande Valley Policy Initiative: May 29, 2026 Registration due; June 5, 2026 Proposal due

     

The Hogg Foundation for Mental Health seeks to advance mental wellness for the people of Texas by investing in programs, policy analysis, research, and education through grants, scholarships…

The CARES Foundation

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Application Deadline:
  • Letters of inquiry: May 29, 2026
  • Invited proposals: July 31, 2026
Grant Range:
$10000 - $302163
Average Grant:
$122222

The CARES Foundation supports nonprofit organizations in the greater Sacramento, CA, area.

The Foundation provides grants to organizations that serve the needs of people with HIV/AIDS, aid…

Indosuez Foundation

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Application Deadline:
  • Projects based in France: April 30, 2026
  • Projects based outside of France: May 31, 2026

The Indosuez Foundation in Europe, under the Fondation de France, supports nonprofit organizations working to promote the social inclusion of vulnerable populations in Europe.

The…

Substance abuse is a national epidemic, as are mental disorders relating to consistent patterns of abuse. It is estimated that over 20 million adult Americans have some sort of substance use disorder. Substance abuse itself leads to a wide range of other health and social issues. This is why many nonprofits have dedicated themselves to the fight against substance abuse disorders.

These nonprofits can only do their work, however, thanks to the generous funding provided by substance abuse grants. These grants can be put towards a wide range of purposes. These could include funding detox programs, rehabilitation centers, prevention programs and harm reduction programs.

There are many organizations that might be providing substance use grants at any given time. Traditionally, this included federal organizations such as the Substance Abuse and Mental Health Services Administration. There are also many private foundations involved in this space, such as the Robert Wood Johnson Foundation and the Open Society Foundations. 

When drafting substance use disorder grant proposals, it's important to use extensive and accurate data. You need to make a case that there is a specific need in a specific community, and that your nonprofit can address that need. Statistics could include prevalence rates of substance abuse disorders, overdose statistics and treatment access gaps. Good places to start looking could include the National Institute on Drug Abuse and Centers for Disease Control and Prevention. 

If you need further insights on drafting great substance use disorder grants, then make sure to check out our great overview of the topic. You can also start browsing a comprehensive list of substance abuse grants right here, all open for applications.